Invitrogen™ SUV420H2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115484

Catalog No. PIPA5115484

Description

Antibody detects endogenous levels of total KMT5C/SUV4-20h2.

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Specifications

• Antigen: SUV420H2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT5C
• Gene Alias: BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 232811, 308345, 84787
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P0C2N6, Q6Q783, Q86Y97
• Gene Symbols: KMT5C
• Immunogen: A synthesized peptide derived from human KMT5C(Accession Q86Y97), corresponding to amino acid residues H92-I142.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG