Invitrogen™ SUV420H2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5145093

Catalog No. FEPA5145093

Description

Immunogen sequence: THKMNVSPVP PLRRQQHLRS ALETFLRQRD LEAAYRALTL GGWTARYFQS R Antigen sequence identity: Mouse 88%; Rat 86%.

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Specifications

• Antigen: SUV420H2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT5C
• Gene Alias: BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84787
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86Y97
• Gene Symbols: KMT5C
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 31-81. Recombinant protein control fragment (Product #RP-110078).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid