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Invitrogen™ SUV420H2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA513436
Description
This antibody is predicted to react with rat based on sequence homology.
SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
Specifications
SUV420H2 | |
Polyclonal | |
Unconjugated | |
KMT5C | |
BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2 | |
Rabbit | |
Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
RUO | |
232811, 84787 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Flow Cytometry, Western Blot | |
2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
Q6Q783, Q86Y97 | |
KMT5C | |
KLH conjugated synthetic peptide between 195-220 amino acids of human SUV4-20H2. | |
200 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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