Suz12 Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3724	Active Motif 91164	10 μg
50-199-3716	Active Motif 91163	100 μg

Description

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Specifications

• Antigen: Suz12
• Applications: Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: Q15022
• Gene ID (Entrez): 23512
• Immunogen: This antibody was raised against full length human SUZ12 (suppressor of zeste 12 homolog (Drosophila)
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: SUZ12

• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
• Gene Alias: 2610028O16Rik; AI195385; AU016842; AW536442; ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; KIAA0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit
• Gene Symbols: SUZ12
• Isotype: IgG2a
• Purification Method: Protein A
• Product Type: Antibody