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SV40 Large T-Antigen Monoclonal Antibody (PAb101 (412)), Invitrogen™

Catalog No. PIMA512458
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Quantity:
500 μL
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Catalog No. Quantity
PIMA512458 500 μL
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Catalog No. PIMA512458 Supplier Thermo Scientific Supplier No. MA512458

Description

Mouse Monoclonal Antibody

This antibody reacts with native and denatured large T-antigen. It does not react with the small T-antigen of SV40 or the large T-antigen of BKV, human papovavirus.

The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SV40 Large T-Antigen
Applications Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone PAb101 (412)
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Alias simian vacuolating virus 40; simian virus; Simian virus 40; sv40 large t antigen; sv40 virus large t antigen
Host Species Mouse
Immunogen SV40 transformed mouse line B4
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2a
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