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Invitrogen™ SV40 T-Antigen Monoclonal Antibody (PAb416)
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Catalog No. PIMA190661
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500 μL
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Catalog No. Quantity
PIMA190661 500 μL
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Catalog No. PIMA190661 Supplier Invitrogen™ Supplier No. MA190661
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Description

Mouse Monoclonal Antibody

This antibody recognizes the 94 kDa SV40 large T antigen and the 20.5 kDa SV40 small T antigen. Recommended positive controls include SV80 or SV-T2 cells.

The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
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Specifications

Antigen SV40 T-Antigen
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone PAb416
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation 0.05M sodium phosphate with 0.2% gelatin and 0.1% sodium azide
Gene Alias simian vacuolating virus 40; simian virus; Simian virus 40; SV40 T-antigen; sv40 virus large t antigen
Host Species Mouse
Immunogen Full length protein (purified) (SV40).
Purification Method Antigen affinity chromatography
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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