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Invitrogen™ Synapsin 1 Polyclonal Antibody
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Catalog No. OPA104001
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50 μL
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OPA104001 50 μL
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Catalog No. OPA104001 Supplier Invitrogen™ Supplier No. OPA104001
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Description

Rabbit Polyclonal Antibody

In Western blot, this antibody detects an ~77 kDa and ~80 kDa protein representing synapsin I alpha and synapsin I beta respectively, in rat brain homogenate. Immunohistochemical staining of synapsin 1 alpha and 1 beta in human brain with OPA1-04001 yields a pattern consistent with cytoplasmic vesicle staining.

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Synapsin 1
Applications Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with no preservative
Gene SYN1
Gene Accession No. O88935, P09951, P17599, P17600
Gene Alias Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S
Gene Symbols SYN1
Host Species Rabbit
Immunogen Native protein purified from bovine brain.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20964, 24949, 281510, 6853
Target Species Human, Mouse, Rat, Bovine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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