Invitrogen™ Synapsin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556976

Catalog No. PIPA556976

Description

Immunogen sequence: SDSSFMANLP NGYMTDLQRP DSSTSSPASP AMERRHPQPL AASFSSPGSS LFSSLSSAMK QAPQATSGLM EPPGPSTPIV QRPRILLVID DAHTDWSKYF HGKKVNGEIE IRVEQAEFSE LNLAAYVTGG CMVDMQVVRN Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction.

Specifications

• Antigen: Synapsin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYN3
• Gene Alias: cN28H9.2 (synapsin III); Syn3; synapsin 3; synapsin III; synapsin IIIa; synapsin-3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8224
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14994
• Gene Symbols: SYN3
• Immunogen: Recombinant protein corresponding to Human Synapsin 3. Recombinant protein control fragment (Product #RP-91528).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG