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Synaptogyrin 3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981310
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50-198-1310 100 μL
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Catalog No. 50-198-1310 Supplier Bioss Supplier No. BS11373R
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Rabbit Polyclonal Antibody

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.

Specifications

Antigen Synaptogyrin 3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SYNGR3
Gene Accession No. O43761
Gene Alias Sgyr III; synaptogryin III; synaptogyrin 3; Synaptogyrin-3; SYNGR3
Gene Symbols SYNGR3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Synaptogyrin 3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9143
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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