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Invitrogen™ Synaptophysin Monoclonal Antibody (7H12)
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Catalog No. PIMA515623
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100 μL
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Catalog No. Quantity
PIMA515623 100 μL
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Catalog No. PIMA515623 Supplier Invitrogen™ Supplier No. MA515623
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Description

Mouse Monoclonal Antibody

MA5-15623 targets SYP in indirect ELISA, IHC and WB applications and shows reactivity with Human and Rat samples. The MA5-15623 immunogen is purified recombinant fragment of SYP expressed in E. Coli. MA5-15623 detects SYP which has a predicted molecular weight of approximately 33.8kDa.

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Synaptophysin
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 7H12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene Syp
Gene Accession No. P07825, P08247, Q62277
Gene Alias A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
Gene Symbols Syp
Host Species Mouse
Immunogen Purified recombinant fragment of SYP expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20977, 24804, 6855
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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