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Synaptophysin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA516417
Description
PA5-16417 targets Synaptophysin in IHC (P) and WB applications and shows reactivity with Rat and Human samples. The PA5-16417 immunogen is a synthetic peptide from C-terminus of human synaptophysin.
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
Specifications
Synaptophysin | |
Polyclonal | |
Unconjugated | |
Syp | |
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1 | |
Rabbit | |
Protein A | |
RUO | |
20977, 24804, 6855 | |
4° C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
P07825, P08247, Q62277 | |
Syp | |
A synthetic peptide from C-terminus of human synaptophysin | |
500 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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