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Invitrogen™ Synaptopodin Polyclonal Antibody
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Catalog No. PIPA597078
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100 μL
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PIPA597078 100 μL
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Catalog No. PIPA597078 Supplier Invitrogen™ Supplier No. PA597078
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLGPHLPPPP LAPSEGRPTP CAFQIPDGSY RCLALEAEES SGEEGLQGEV GPTDLEEDEG VSRSGDDSAC RVTQGTPQLP KALGIQPPSC SREEQGASQH DDRASQDWDV VKAGQMMTAS PSPGPGPRVA QKPALGRSTS LTEKDLKEAK ARSQQIAAQL TTPPSSNSRG VQLFNRRRQR VNEFTLESHG QRGQKPSQES LRVLPSSLPG HAPGLSLSST SLPEPGPPRH PSPQSPDRGV PGHSMEGYSE EASLLRHLEK; Positive Samples: 293T, HeLa, U-87MG, Rat brain; Cellular Location: Cell junction, Cell projection, Cytoplasm, Perikaryon, cytoskeleton, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse, tight junction.

SYNPO (Synaptopodin) is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Synaptopodin
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SYNPO
Gene Accession No. Q8CC35, Q8N3V7, Q9Z327
Gene Alias 9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661; KIAA1029; Synaptopodin; SYNPO
Gene Symbols SYNPO
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SYNPO (NP_0011596801).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104027, 11346, 60324
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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