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Invitrogen™ Syncollin Polyclonal Antibody
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Catalog No. PIPA561563
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100 μL
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PIPA561563 100 μL
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Catalog No. PIPA561563 Supplier Invitrogen™ Supplier No. PA561563
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Rabbit Polyclonal Antibody

Immunogen sequence: TASSLVVAPR CELTVWSRQG KAGKTHKFSA GTYPRLEEYR RGILGDWSNA ISALYCRCP Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 71%.

Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds. Syncollin is also known to associate with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and also plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have a pore-forming activity on membranes and regulate exocytosis insome exocrine tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Syncollin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SYCN
Gene Accession No. Q0VAF6
Gene Alias 0910001K16Rik; 1810038B08Rik; FLJ27441; INSSA1; insulin synthesis associated 1; insulin synthesis-associated protein 1; Proximal small intestine-specific protein 9; Sip9; Sycn; SYL; syncollin
Gene Symbols SYCN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Syncollin. Recombinant protein control fragment (Product #RP-99213).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 342898
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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