Invitrogen™ Syndecan 4 Recombinant Rabbit Monoclonal Antibody (008)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA531167

Catalog No. PIMA531167

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse SDC4/Syndecan-4.

Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.

Specifications

• Antigen: Syndecan 4
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O35988
• Gene Symbols: Sdc4
• Immunogen: Recombinant Mouse SDC4/Syndecan-4 protein (Met1-Val146).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunocytochemistry
• Clone: 008
• Conjugate: Unconjugated
• Gene: Sdc4
• Gene Alias: AA959608; Amphiglycan; AW108331; MGC22217; RATRYUDOCA; RYUDOCA; ryudocan; ryudocan amphiglycan; ryudocan core protein; Ryudocan/syndecan 4; S4; SDC4; Synd4; syndecan 4; syndecan 4 (amphiglycan, ryudocan); syndecan proteoglycan 4; syndecan-4
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20971
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid