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Invitrogen™ SynGAP Recombinant Rabbit Monoclonal Antibody (8M2S9)
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Catalog No. PIMA542710
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Quantity:
100 μL
Catalog No. Quantity
PIMA542710 100 μL
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Catalog No. PIMA542710

Supplier: Invitrogen™ MA542710

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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: Mouse brain, Rat brain. Immunogen sequence: SEKRLRQQQA EKDSQIKSII GRLMLVEEEL RRDHPAMAEP LPEPKKRLLD AQERQLPPLG PTNPRVTLAP PWNGLAPPAP PPPPRLQITE NGEFRNTADH.

Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. SynGAP has been shown to be a major component of postsynaptic density and associates with post synaptic density 95 kDa (PSD-95), a synaptic scaffold protein, and synaptic N-methyl-D-aspartate (NMDA) receptors. SynGAP Ras-GTPase activity has also been shown to be inhibited by phosphorylation by CaM kinase II, another abundant protein located in the postsynaptic density. It has been proposed that SynGAP may function as a negative regulator of MAP Kinase activation in the absence of active NMDA receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SynGAP
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 8M2S9
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SYNGAP1
Gene Accession No. F6SEU4, Q96PV0, Q9QUH6
Gene Alias DKFZp761G1421; Gm1963; KIAA1938; MRD5; Neuronal R; Neuronal RasGAP; OTTHUMP00000209046; p135 SynGAP; Ras GTPase-activating protein SynGAP; ras/Rap GTPase-activating protein SynGAP; RASA1; RASA5; synaptic Ras GTPase activating protein 1; synaptic Ras GTPase activating protein 1 homolog; synaptic Ras GTPase activating protein 1 homolog (rat); synaptic Ras GTPase activating protein, 135kDa; synaptic Ras GTPase-activating protein 1; Synaptic Ras-GAP 1; SYNGAP; Syngap1
Gene Symbols SYNGAP1
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192117, 240057, 8831
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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