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Invitrogen™ SynGAP Recombinant Rabbit Monoclonal Antibody (HL2292)
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Catalog No. FEMA550478
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100 μL
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FEMA550478 100 μL
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Catalog No. FEMA550478 Supplier Invitrogen™ Supplier No. MA550478
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Rabbit Recombinant Monoclonal Antibody

SynGAP Recombinant Monoclonal Antibody for Western Blot, ICC/IF

Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. SynGAP has been shown to be a major component of postsynaptic density and associates with post synaptic density 95 kDa (PSD-95), a synaptic scaffold protein, and synaptic N-methyl-D-aspartate (NMDA) receptors. SynGAP Ras-GTPase activity has also been shown to be inhibited by phosphorylation by CaM kinase II, another abundant protein located in the postsynaptic density. It has been proposed that SynGAP may function as a negative regulator of MAP Kinase activation in the absence of active NMDA receptors.
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Specifications

Antigen SynGAP
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2292
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene SYNGAP1
Gene Accession No. F6SEU4, Q9QUH6
Gene Alias DKFZp761G1421; Gm1963; KIAA1938; MRD5; Neuronal R; Neuronal RasGAP; OTTHUMP00000209046; p135 SynGAP; Ras GTPase-activating protein SynGAP; ras/Rap GTPase-activating protein SynGAP; RASA1; RASA5; synaptic Ras GTPase activating protein 1; synaptic Ras GTPase activating protein 1 homolog; synaptic Ras GTPase activating protein 1 homolog (rat); synaptic Ras GTPase activating protein, 135kDa; synaptic Ras GTPase-activating protein 1; Synaptic Ras-GAP 1; SYNGAP; Syngap1
Gene Symbols SYNGAP1
Host Species Rabbit
Immunogen Recombinant fragmemt of human SYNGAP1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192117, 240057
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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