Invitrogen™ SYNGR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589618

Catalog No. PIPA589618

Description

Immunogen sequence: MEGGAYGAGK AGGAFDPYTL VRQPHTILRV VSWLFSIVVF GSIVNEGYLN SASEGEEFCI YNRNPNACSY GVAVGVLAFL TCLLYLALDV YFPQISSVKD RKKAVLSDIG VSAFWAFLWF VGFCYLANQW QVSKPKDNPL NEGTDAARAA IAFSFFSIFT WSLTAALAVR RFKDLSFQEE YSTLFPASAQ P; Positive Samples: Mouse pancreas, Rat brain; Cellular Location: Cell junction, Melanosome, Membrane, Multi-pass membrane protein, synapse.

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Specifications

• Antigen: SYNGR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Syngr1
• Gene Alias: p29; R75468; RP3-333H23.3; synaptogyrin 1; synaptogyrin-1; Syngr1; Syngr1b
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20972, 29205
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O55100, Q62876
• Gene Symbols: Syngr1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human SYNGR1 (NP_6637831).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG