Invitrogen™ Synip Monoclonal Antibody (J.696.2)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514940

Catalog No. PIMA514940

Description

It is not recommended to aliquot this antibody.

STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

Specifications

• Antigen: Synip
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: Stxbp4
• Gene Alias: 6030470M02Rik; FLJ16496; MGC149829; MGC50337; STX4-interacting protein; Stxbp4; Synip; syntaxin 4 interacting protein; syntaxin 4-interacting protein; syntaxin binding protein 4; syntaxin-binding protein 4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20913, 252983, 303443
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Clone: J.696.2
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: Q6ZWJ1, Q9WV89
• Gene Symbols: Stxbp4
• Immunogen: Synthetic peptide corresponding to the sequence of human Synip.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG