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Invitrogen™ Synip Polyclonal Antibody
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Catalog No. PIPA555020
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100 μL
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PIPA555020 100 μL
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Catalog No. PIPA555020 Supplier Invitrogen™ Supplier No. PA555020
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPLGRNGRSI PATLALESKE LVKSVRALLD MDCLPYGWEE AYTADGIKYF INHVTQTTSW IHPVMSVLNL SRSEENEEDC SRELPNQK Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 81%.

STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Synip
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Stxbp4
Gene Accession No. Q6ZWJ1
Gene Alias 6030470M02Rik; FLJ16496; MGC149829; MGC50337; STX4-interacting protein; Stxbp4; Synip; syntaxin 4 interacting protein; syntaxin 4-interacting protein; syntaxin binding protein 4; syntaxin-binding protein 4
Gene Symbols Stxbp4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Synip. Recombinant protein control fragment (Product #RP-93362).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 252983
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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