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Synoviolin Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501563876
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20 μL; Unconjugated
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Catalog No.
50-156-3876 20 μL; Unconjugated
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Catalog No. 50-156-3876 Supplier Bethyl Laboratories, Inc Supplier No. A302946AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.

Specifications

Antigen Synoviolin
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SYVN1
Gene Accession No. Q86TM6, Q9DBY1
Gene Alias HRD1, KIAA1810, MGC40372
Gene Symbols Syvn1
Host Species Rabbit
Immunogen Between 567 and 617
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74126, 84447
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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