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Synoviolin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501563873
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50-156-3873 10 μL
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Catalog No. 50-156-3873 Supplier Bethyl Laboratories, Inc Supplier No. A302945AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.

Specifications

Antigen Synoviolin
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene SYVN1
Gene Accession No. Q86TM6
Gene Alias HRD1, KIAA1810, MGC40372
Gene Symbols SYVN1
Host Species Rabbit
Immunogen Between 550 and 600
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84447
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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