Invitrogen™ SYNPO Polyclonal Antibody

Catalog No.	Quantity
PIPA556997	100 μL

Catalog No. PIPA556997 Supplier Invitrogen™ Supplier No. PA556997

Description

Rabbit Polyclonal Antibody

Immunogen sequence: TTPTKVYSEV HFTLAKPPSV VNRTARPFGI QAPGGTSQME RSPMLERRHF GEKAPAPQPP SLPDRSPRPQ RHIMSRSPMV ERRMMGQRS Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

SYNPO (Synaptopodin) is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.

Specifications

• Antigen: SYNPO
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: SYNPO
• Gene Accession No.: Q8N3V7
• Gene Alias: 9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661; KIAA1029; Synaptopodin; SYNPO
• Gene Symbols: SYNPO
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human SYNPO. Recombinant protein control fragment (Product #RP-95703).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11346
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov