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Invitrogen™ SYNPO2L Polyclonal Antibody
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Catalog No. PIPA563082
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100 μL
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PIPA563082 100 μL
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Catalog No. PIPA563082 Supplier Invitrogen™ Supplier No. PA563082
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PAEALLLPHG PLRPGPHLIP MVGPVPHPVA EDLTTTYTQK AKQAKLQRAE SLQEKSIKEA KTKCRTIASL LTA Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 99%.

SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SYNPO2L
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SYNPO2L
Gene Accession No. Q9H987
Gene Alias 1110054M18Rik; Chap; RGD1565434; synaptopodin 2 like; synaptopodin 2-like; synaptopodin 2-like protein; SYNPO2L
Gene Symbols SYNPO2L
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SYNPO2L. Recombinant protein control fragment (Product #RP-101447).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79933
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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