Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ Syntaxin 1 Monoclonal Antibody (SP8)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA547694
Description
Specific for endogenous levels of the ~36 kDa syntaxin protein. The antibody has also been used for immunohistochemistry on formalin fixed, vibratome sections. *Does not work on paraffin sections.
Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications
Syntaxin 1 | |
Monoclonal | |
1 mg/mL | |
10mM HEPES with 100μg/mL BSA, 50% glycerol, 150mM NaCl and no preservative; pH 7.5 | |
P32851, Q16623 | |
Stx1a | |
Synaptic immunoprecipitate (crude) from human brain. | |
100 μL | |
Primary | |
Human, Rat, Pig | |
Antibody | |
IgG1 |
Immunohistochemistry (Frozen), Western Blot | |
SP8 | |
Unconjugated | |
Stx1a | |
HPC-1; LOW QUALITY PROTEIN: syntaxin-1A; neuron-specific antigen HPC-1; P35-1; P35A; Sap; STX1; Stx1a; STX1B; STX1B1; STX1B2; STXA1; SYN1A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2 | |
Mouse | |
Protein G | |
RUO | |
100512594, 116470, 6804 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction