Invitrogen™ Syntaxin 1 Monoclonal Antibody (SP8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA517615

Catalog No. PIMA517615

Description

MA5-17615 targets Syntaxin-1A in ELISA, FACS, and WB applications and shows reactivity with Human, Mouse, Porcine, and Rat samples. The MA5-17615 immunogen is human Syntaxin.

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Syntaxin 1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O35526, P32851, Q16623
• Gene Symbols: Stx1a
• Immunogen: Human Syntaxin.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: SP8
• Conjugate: Unconjugated
• Gene: Stx1a
• Gene Alias: HPC-1; LOW QUALITY PROTEIN: syntaxin-1A; neuron-specific antigen HPC-1; P35-1; P35A; Sap; STX1; Stx1a; STX1B; STX1B1; STX1B2; STXA1; SYN1A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 116470, 20907, 6804
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov