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Invitrogen™ Syntaxin 1 Polyclonal Antibody
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Catalog No. PIPA528431
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100 μL
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PIPA528431 100 μL
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Catalog No. PIPA528431 Supplier Invitrogen™ Supplier No. PA528431
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4. Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Syntaxin 1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 9.3 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Stx1a
Gene Accession No. P32851, Q16623
Gene Alias HPC-1; LOW QUALITY PROTEIN: syntaxin-1A; neuron-specific antigen HPC-1; P35-1; P35A; Sap; STX1; Stx1a; STX1B; STX1B1; STX1B2; STXA1; SYN1A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2
Gene Symbols Stx1a
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Intracellular domain of human Syntaxin 1a. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116470, 6804
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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