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Invitrogen™ Syntaxin 1 Recombinant Mouse Monoclonal Antibody (SP6)
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Catalog No. PIMA547883
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200 μg
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Catalog No. Quantity
PIMA547883 200 μg
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Catalog No. PIMA547883 Supplier Invitrogen™ Supplier No. MA547883
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Description

Mouse Recombinant Monoclonal Antibody

Specificity: This antibody binds to native and denatured syntaxin.

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Syntaxin 1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Recombinant Monoclonal
Clone SP6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Stx1a
Gene Accession No. P32850, P32851, Q16623
Gene Alias HPC-1; LOW QUALITY PROTEIN: syntaxin-1A; neuron-specific antigen HPC-1; P35-1; P35A; Sap; STX1; Stx1a; STX1B; STX1B1; STX1B2; STXA1; SYN1A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2
Gene Symbols Stx1a
Host Species Mouse
Immunogen Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100008772, 100512594, 100727115, 100759989, 100855965, 116470, 6804, 788566
Target Species Human, Rat, Canine, Rabbit, Bovine, Hamster, Pig, Guinea Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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