Invitrogen™ Syntaxin 6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115981

Catalog No. PIPA5115981

Description

Antibody detects endogenous levels of total STX6.

Syntaxin 6 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. Syntaxin is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Syntaxin 6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STX6
• Gene Alias: 2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; HGNC:11441; STX6; Syn6; syntaxin 6; syntaxin-6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10228, 58244, 60562
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O43752, Q63635, Q9JKK1
• Gene Symbols: STX6
• Immunogen: A synthesized peptide derived from human STX6(Accession O43752), corresponding to amino acid residues Q168-V218.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG