Invitrogen™ Syntenin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528813

Catalog No. PIPA528813

Description

Recommended positive controls: U87-MG. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: Syntenin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SDCBP
• Gene Alias: MDA9; MDA-9; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; Pro-TGF-alpha cytoplasmic domain-interacting protein 18; sb:eu862; Scaffold protein Pbp1; sdcbp; si:dkey-235k4.1; ST1; Sycl; syndecan binding protein; syndecan binding protein (syntenin); syndecan interacting protein; syndecan-binding protein; syndecan-binding protein 1; syntenin; syntenin 1; syntenin-1; syntenin-b; TACIP18; Unknown (protein for MGC:128349)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 407719, 53378, 6386
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00560, O08992
• Gene Symbols: SDCBP
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human Syntenin 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Zebrafish
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov