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Syntrophin-3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980844
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50-198-0844 100 μL
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Catalog No. 50-198-0844 Supplier Bioss Supplier No. BS10385R
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Rabbit Polyclonal Antibody

Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.

Specifications

Antigen Syntrophin-3
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SNTB2
Gene Accession No. Q13425
Gene Alias 59 kDa dystrophin-associated protein A1 basic component 2; Beta-2-syntrophin; D16S2531E; dystrophin-associated protein A1, 59kD, basic component 2; EST25263; Snt2; Snt2b2; SNT3; SNTB2; SNTL; SYN; syntrophin beta 2; syntrophin, basic 2; syntrophin, beta 2; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); Syntrophin-3; Syntrophin-like
Gene Symbols SNTB2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Syntrophin-3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6645
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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