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Invitrogen™ SYT10 Polyclonal Antibody
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Catalog No. PIPA5104173
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100 μL
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PIPA5104173 100 μL
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Catalog No. PIPA5104173 Supplier Invitrogen™ Supplier No. PA5104173
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SYT10.

SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SYT10
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SYT10
Gene Accession No. O08625, Q6XYQ8, Q9R0N4
Gene Alias DKFZp781D2042; P65; SVP65; synaptotagmin 10; synaptotagmin X; Synaptotagmin-10; SYT; Syt10; SYT-10; SytX
Gene Symbols SYT10
Host Species Rabbit
Immunogen A synthesized peptide derived from human SYT10(Accession Q6XYQ8), corresponding to amino acid residues R417-C467.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 341359, 54526, 60567
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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