Invitrogen™ SYT10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104173

Catalog No. PIPA5104173

Description

Antibody detects endogenous levels of total SYT10.

SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.

Specifications

• Antigen: SYT10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYT10
• Gene Alias: DKFZp781D2042; P65; SVP65; synaptotagmin 10; synaptotagmin X; Synaptotagmin-10; SYT; Syt10; SYT-10; SytX
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 341359, 54526, 60567
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O08625, Q6XYQ8, Q9R0N4
• Gene Symbols: SYT10
• Immunogen: A synthesized peptide derived from human SYT10(Accession Q6XYQ8), corresponding to amino acid residues R417-C467.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov