Invitrogen™ SYT10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563126

Catalog No. PIPA563126

Description

Immunogen sequence: MSFHKEDGVN SLCQKALHIV TELCFAGQVE WEKCSGIFPR DRGSQGGSST DIS Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.

Specifications

• Antigen: SYT10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYT10
• Gene Alias: DKFZp781D2042; P65; SVP65; synaptotagmin 10; synaptotagmin X; Synaptotagmin-10; SYT; Syt10; SYT-10; SytX
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 341359
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6XYQ8
• Gene Symbols: SYT10
• Immunogen: Recombinant protein corresponding to Human SYT10. Recombinant protein control fragment (Product #RP-101200).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG