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Invitrogen™ SYT10 Polyclonal Antibody
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Catalog No. PIPA563126
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100 μL
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PIPA563126 100 μL
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Catalog No. PIPA563126 Supplier Invitrogen™ Supplier No. PA563126
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSFHKEDGVN SLCQKALHIV TELCFAGQVE WEKCSGIFPR DRGSQGGSST DIS Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

SYT10 is a Ca2+ sensor specifically required for the Ca2+-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. SYT10 is not involved in Ca2+-dependent synaptic vesicle exocytosis. It acts through Ca2+ and phospholipid binding to the C2 domain: Ca2+ induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SYT10
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SYT10
Gene Accession No. Q6XYQ8
Gene Alias DKFZp781D2042; P65; SVP65; synaptotagmin 10; synaptotagmin X; Synaptotagmin-10; SYT; Syt10; SYT-10; SytX
Gene Symbols SYT10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SYT10. Recombinant protein control fragment (Product #RP-101200).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 341359
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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