Invitrogen™ SYT12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544988

Catalog No. PIPA544988

Description

Peptide sequence: AEAREKRVPA WNAQRASTRG PPSRKGSLSI EDTFESISEL GPLELMGREL Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%.

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.

Specifications

• Antigen: SYT12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYT12
• Gene Alias: Srg1; synaptotagmin 12; synaptotagmin XII; Synaptotagmin12; Synaptotagmin-12; synaptotagmin-related gene 1 protein; SynaptotagminXII; synaptotagmin-XII; Syt XII; SYT11; Syt12; SYT-12; Sytr1; SytXII
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91683
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IV01
• Gene Symbols: SYT12
• Immunogen: Synthetic peptide directed towards the N-terminal of human SYT12 (aa 71-120).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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