Invitrogen™ SYTL5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521176

Catalog No. PIPA521176

Description

A suggested positive control is Hela cell lysate. PA5-21176 can be used with blocking peptide PEP-1290.

SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.

Specifications

• Antigen: SYTL5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SYTL5
• Gene Alias: ENSMUSG00000054453; exophilin 9; Slp5; synaptotagmin 15; synaptotagmin like 5; synaptotagmin-like 5; synaptotagmin-like protein 5; Sytl5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 236643, 302538, 94122
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q80T23, Q812E4, Q8TDW5
• Gene Symbols: SYTL5
• Immunogen: A 17 amino acid peptide near the amino terminus of human SYTL5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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