SYVN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-557-919	Proteintech Group Inc 134731AP150UL	150 μL

Description

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.

Specifications

• Antigen: SYVN1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q86TM6, Q9DBY1
• Gene ID (Entrez): 361712, 74126, 84447
• Immunogen: SYVN1 Fusion Protein Ag4267
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SYVN1

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: HRD1, KIAA1810, Synovial apoptosis inhibitor 1, SYVN1
• Gene Symbols: Syvn1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody