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SYVN1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980441
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100 μL
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Catalog No. Quantity
50-198-0441 100 μL
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Catalog No. 50-198-0441 Supplier Bioss Supplier No. BS0679R
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Description

Rabbit Polyclonal Antibody

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.

Specifications

Antigen SYVN1
Applications Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SYVN1
Gene Accession No. Q86TM6
Gene Alias 1200010C09Rik; AW211966; C85322; D530017H19Rik; DER3; E3 ubiquitin-protein ligase synoviolin; HMG-coA reductase degradation 1 homolog; HRD1; HRD1 protein; KIAA1810; MGC40372; RGD1310488; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1; synovial apoptosis inhibitor 1, synoviolin; synoviolin 1; Syvn1
Gene Symbols SYVN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SYVN1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84447
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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