γδ T-Cell Receptor Hamster anti-Mouse, Brilliant Violet 605, Clone: GL3, BD Optibuild™

Armenian Hamster Monoclonal Antibody

Supplier:  BD Biosciences 744116

Catalog No. BDB744116

Description

The GL3 monoclonal antibody specifically binds to a common epitope of theδchain of the T-cell Receptor (TCR) complex onγδTCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react withαβTCR-bearing T cells. In the mouse, cells expressing theγδTCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonsry epithelium, peritoneum, liver, and peripheral lymphoid organa.

This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max of 602nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20nm filter set. BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers. BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser. BV605 is a tandem fluorochrome that combines BD Horizon BV421 and Cy™3.5. These conjugates are very bright, exhibiting similar brightness to equivalent PE conjugates. Due to the excitation of Cy3.5 by the green (532nm) and yellow-green (561nm) lasers, there will be significant spillover of the BD Horizon BV605 signal into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers.

Specifications

• Antigen: γδ T-Cell Receptor
• Clone: GL3
• Conjugate: Brilliant Violet 605
• Gene Alias: Tcrd, T-cell receptor delta chain, Tcr delta
• Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Armenian Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov