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Description
The R73 antibody reacts with the αβ T-cell Receptor (TCR) found on most peripheral T lymphocytes, intestinal intraepithelial lymphocytes, and thymocytes. It does not react with γδ TCR-bearing cells. Cross-linked R73 mAb induces T-cell differentiation and activation. In vivo treatment with mAb R73 can suppress immune function of peripheral αβ TCR-expressing T cells, and reduce the severity of experimental autoimmune, transplant rejection, and graft-versus-host responses.
Specifications
Specifications
| Antigen | αβ T-Cell Receptor |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | R73 |
| Concentration | 0.5mg/mL |
| Conjugate | FITC |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rat T blasts and rat erythrocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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