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Tocris Bioscience™ t-TUCB
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Catalog No. 67575 Shop All Novus Biologicals Products
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67-575 5 mg
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Catalog No. 67-575 Supplier Tocris Bioscience™ Supplier No. 6757/5
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Description

Potent soluble epoxide hydrolase (sEH) Inhibitor; anti-inflammatory and antinociceptive

t-TUCB is a potent soluble epoxide hydrolase (sEH) Inhibitor (IC50 = 0.9 nM). Enhances hepatic eNOS phosphorylation and NO release. Exhibits antihypertensive and cardioprotective actions in cirrhotic rat models. Suppress the activation of HSCs and reduce hepatic fibrosis through inhibition of NF-κB/IκBα signaling. Anti-inflammatory and antinociceptive.

Specifications

Chemical Name or Material 4-[[trans-4-[[[[4-(Trifluoromethoxy)phenyl]amino]carbonyl]amino]cyclohexyl]oxy]benzoic acid
CAS 948304-40-3
Quantity 5 mg
Molecular Formula C21H21F3N2O5
Formula Weight 438.4
Product Type Inhibitor
Purity 98%
Product Title
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