TAAL6 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7149	100 μL

Catalog No. 50-198-7149 Supplier Bioss Supplier No. BS6242R

Description

Rabbit Polyclonal Antibody

TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.

Specifications

• Antigen: TAAL6
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TM4SF1
• Gene Accession No.: P30408
• Gene Alias: 12A8 target antigen; H-L6; L6; L6 antigen; M3S1; Membrane component chromosome 3 surface marker 1; Membrane component chromosome 3 surface marker 1 homolog; membrane component, chromosome 3, surface marker 1; membrane component, surface marker 1; TAAL6; TM4SF1; transmembrane 4 L six family member 1; Transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1; Tumor-associated antigen L6
• Gene Symbols: TM4SF1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Transmembrane 4 L6 family member 1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4071
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG