Invitrogen™ TAAR1 Polyclonal Antibody

Catalog No.	Quantity
PIPA533066	50 μg

Catalog No. PIPA533066 Supplier Invitrogen™ Supplier No. PA533066

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Monkey (100%); Orangutan (95%); Gibbon, Marmoset, Elephant (89%); Tamarin, Rabbit, Pig (84%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.

Specifications

• Antigen: TAAR1
• Applications: ELISA, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: Taar1
• Gene Accession No.: Q96RJ0
• Gene Alias: MGC126874; MGC138399; RP11-295F4.9; RTAR1; Snorf33; Ta1; Taar1; TAR1; taR-1; trace amine associated receptor 1; trace amine receptor 1; trace amine-associated receptor 1; trace-amine-associated receptor 1; TRAR1
• Gene Symbols: Taar1
• Host Species: Rabbit
• Immunogen: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human TAAR1.
• Purification Method: Antigen affinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 134864
• Target Species: Human, Monkey
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG