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Invitrogen™ TACC3 Monoclonal Antibody (OTI1E11)
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Catalog No. PIMA525128
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100 μL
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PIMA525128 100 μL
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Catalog No. PIMA525128 Supplier Invitrogen™ Supplier No. MA525128
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Description

Mouse Monoclonal Antibody

TACC3 Monoclonal Antibody for Western Blot, ICC/IF, Flow

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TACC3
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone OTI1E11
Concentration 0.67 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TACC3
Gene Accession No. Q9Y6A5
Gene Alias Aint; Arnt interacting protein; ARNT-interacting protein; C86661; ERIC1; ERIC-1; Tacc3; transforming acidic coiled coil 3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; transforming, acidic coiled-coil containing protein 3
Gene Symbols TACC3
Host Species Mouse
Immunogen Full length human recombinant protein of TACC3 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10460, 360962
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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