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TACC3 Monoclonal Antibody (OTI6F1), TrueMAB™, OriGene
SDP

Catalog No. 501672404
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50-167-2404 100 μL
50-254-2424 30 μL
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Catalog No. 50-167-2404 Supplier OriGene Supplier No. TA501261
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Description

Mouse Monoclonal Antibody

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.

Specifications

Antigen TACC3
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI6F1
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TACC3
Gene Accession No. Q9Y6A5
Gene Alias ERIC-1, ERIC1
Gene Symbols TACC3
Host Species Mouse
Immunogen Full length human recombit protein of human TACC3 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10460
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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