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TACC3 Monoclonal Antibody (OTI6H4), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA501264

Encompass_Preferred

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Catalog No. 50-167-2407


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Description

Description

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Specifications

Specifications

TACC3
Monoclonal
0.55 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9Y6A5
TACC3
Full length human recombit protein of human TACC3 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI6H4
Unconjugated
TACC3
ERIC-1, ERIC1
Mouse
Affinity Chromatography
RUO
10460
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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