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Invitrogen™ TACC3 Recombinant Rabbit Monoclonal Antibody (7S7L2)
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Catalog No. PIMA537929
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PIMA537929 100 μL
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Catalog No. PIMA537929 Supplier Invitrogen™ Supplier No. MA537929
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: 293T Immunogen sequence: MSLQVLNDKN VSNEKNTENC DFLFSPPEVT GRSSVLRVSQ KENVPPKNLA KAMKVTFQTP LRDPQTHRIL SPSMASKLEA PFTQDDTLGL ENSHPVWTQK.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TACC3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7S7L2
Concentration 1.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TACC3
Gene Accession No. Q9JJ11, Q9Y6A5
Gene Alias Aint; Arnt interacting protein; ARNT-interacting protein; C86661; ERIC1; ERIC-1; Tacc3; transforming acidic coiled coil 3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; transforming, acidic coiled-coil containing protein 3
Gene Symbols TACC3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TACC3 (NP_0063331).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10460, 21335, 360962
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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