Invitrogen™ TADA3L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540594

Catalog No. PIPA540594

Description

Peptide sequence: AAVADKKKGL MGPLTELDTK DVDALLKKSE AQHEQPEDGC PFGALTQRLL Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%.

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: TADA3L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TADA3
• Gene Alias: 1110004B19Rik; ADA3; ADA3 homolog; ADA3-like protein; AI987856; alteration/deficiency in activation 3; fa03f04; FLJ20221; FLJ21329; hADA3; mADA3; NGG1; STAF54; Tada3; Tada3l; Transcriptional adapter 3; transcriptional adapter 3-like; transcriptional adaptor 3; transcriptional adaptor 3 (NGG1 homolog, yeast)-like; transcriptional adaptor 3-like isoform b; Unknown (protein for MGC:133915); wu:fa03f04; zgc:63596
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10474
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O75528
• Gene Symbols: TADA3
• Immunogen: Synthetic peptide directed towards the middle region of human TADA3L.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov