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Tocris Bioscience™ Tadalafil
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Catalog No. 631150
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Catalog No. Quantity
63-115-0 50 mg
63-111-0 10 mg
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Catalog No. 63-115-0 Supplier Tocris Bioscience™ Supplier No. 6311/50
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Description

Potent and highly selective PDE5 inhibitor; orally bioavailable

Potent and highly selective PDE5 inhibitor (IC50 = 5 nM). Exhibits > 2000-fold selectivity for PDE5 over PDEs 1,2,3 and 4 and 1000-fold selectivity over PDE6. Reduces blood pressure in hypertensive rats. Also delays tumor growth in a mouse model via inhibition of MDSC-mediated immunosuppression. Orally bioavailable.

Chemical Identifiers

CAS 171596-29-5
Molecular Formula C22H19N3O4

Specifications

Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 389.4
Physical Form Solid
Purity >99%
Molecular Weight (g/mol) 389.411
Chemical Name or Material (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1',2':1,6]pyrido[3,4-b]

Safety and Handling

Recommended Storage Store at -20°C
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