TAF1 Polyclonal Antibody, Bethyl Laboratories

Catalog No.	Quantity
50-156-5320	20 μL

Catalog No. 50-156-5320 Supplier Bethyl Laboratories, Inc Supplier No. A303505AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Golden hamster

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.

Specifications

• Antigen: TAF1
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: TAF1
• Gene Accession No.: P21675
• Gene Alias: BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, N-TAF1, NSCL2, OF, P250, TAF2A, TAFII250, XDP
• Gene Symbols: TAF1
• Host Species: Rabbit
• Immunogen: Between 1800 and 1850
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6872
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG