Invitrogen™ TAF10 Polyclonal Antibody

Catalog No.	Quantity
PIPA5103318	100 μL

Catalog No. PIPA5103318 Supplier Invitrogen™ Supplier No. PA5103318

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TAF10.

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

Specifications

• Antigen: TAF10
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: TAF10
• Gene Accession No.: Q12962, Q8K0H5
• Gene Alias: 30kDa; AU041226; im:6899389; mTAFII30; si:dkey-72l14.8; STAF28; TAF(II)30; TAF10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30 kDa; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa; TAF2A; Taf2h; TAFII30; TAFII-30; TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD; TATA box binding protein associated factor 10; TATA-box binding protein associated factor 10; TBP-related factor 10; transcription initiation factor TFIID 30 kD subunit; transcription initiation factor TFIID 30 kDa subunit; Transcription initiation factor TFIID subunit 10
• Gene Symbols: TAF10
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human TAF10(Accession Q12962), corresponding to amino acid residues P14-L64.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24075, 6881
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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